INTRODUCTION:Knee pain is common in adolescents and adults and is associated with an increased fan risk of developing knee osteoarthritis.The aim of this systematic review was to gather and appraise the cost-effectiveness of treatment approaches for non-osteoarthritic knee pain conditions.METHOD:A systematic review was conducted according to the PR
Background: Altered balance between striatal direct and indirect pathways contributes to early motor, cognitive and psychiatric symptoms in Huntington disease (HD).While degeneration of striatal D2-type dopamine receptor (D2)-expressing indirect pathway medium spiny neurons (iMSNs) occurs prior to that of D1-type dopamine receptor (D1)-expressing d
The smuggling of migrants is not a new phenomenon but in recent years it has attracted increasing international attention.In the last few years, migrant smuggling has become one of the most lucrative types of organized crime in Originals 70s Bootcut the Balkans.This research article focuses on the issue of migrant smuggling as a contemporary transn